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To be reliable, the dosage of activated charcoal needs to go to least 5 times the approximated dose of Plaquenil consumed.

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If carefully powdered, activated charcoal is presented by the stomach tube, after lavage, and within 30 minutes after ingestion of the tablets, it may prevent further intestinal tract absorption of the medication.

“Suppression: 400 milligrams (310 milligrams base) orally on the exact same day each week Suppressive treatment must start 2 weeks before exposure; however, failing this, a preliminary dose of 800 milligrams (620 milligrams base) could be taken in 2 divided dosages (6 hours apart).”